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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHD3 All Species: 9.7
Human Site: T1595 Identified Species: 17.78
UniProt: Q12873 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12873 NP_001005271.2 2000 226592 T1595 R I G E K M E T E A D A P S P
Chimpanzee Pan troglodytes XP_512012 1846 210165 T1532 R A S S P T K T S P T T P E A
Rhesus Macaque Macaca mulatta XP_001111066 1981 224269 T1577 R I G E K M D T E V D A P S P
Dog Lupus familis XP_536627 1977 223828 T1571 R T G E K I E T E A D A P S P
Cat Felis silvestris
Mouse Mus musculus Q6PDQ2 1915 217732 P1590 A T V E C A Q P P A P A P A T
Rat Rattus norvegicus Q9JIX5 2581 290674 E2042 R L T P Q D Y E I R V A S S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q06A37 3011 338194 C2207 D K D T K Q D C D A E A E T G
Frog Xenopus laevis NP_001080504 1893 214670 D1568 P V K E E T T D N E V K P T E
Zebra Danio Brachydanio rerio B0R0I6 2511 279693 E1849 Q R W T R R E E C D F Y R V V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O97159 1982 224182 Q1594 A E K S E V K Q E Q E A E E D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22516 1787 205237 I1441 N L P G M I K I K E E P I D I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9S775 1384 158387 K1070 L R S G K I W K E E H D K I M
Baker's Yeast Sacchar. cerevisiae P32657 1468 168223 D1153 L I N S N Y K D D P L K F S L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.3 97.8 97.3 N.A. 67.6 22.6 N.A. N.A. 23.4 66 22.7 N.A. 55 N.A. 47.2 N.A.
Protein Similarity: 100 90.5 98.1 98 N.A. 78.3 37.6 N.A. N.A. 37.2 77.1 38.5 N.A. 68.6 N.A. 61.7 N.A.
P-Site Identity: 100 20 86.6 86.6 N.A. 26.6 20 N.A. N.A. 20 13.3 6.6 N.A. 13.3 N.A. 0 N.A.
P-Site Similarity: 100 26.6 93.3 93.3 N.A. 40 33.3 N.A. N.A. 46.6 33.3 20 N.A. 40 N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 29 26 N.A.
Protein Similarity: N.A. N.A. N.A. 42.6 40.2 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 8 0 0 0 8 0 0 0 31 0 54 0 8 8 % A
% Cys: 0 0 0 0 8 0 0 8 8 0 0 0 0 0 0 % C
% Asp: 8 0 8 0 0 8 16 16 16 8 24 8 0 8 16 % D
% Glu: 0 8 0 39 16 0 24 16 39 24 24 0 16 16 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 0 % F
% Gly: 0 0 24 16 0 0 0 0 0 0 0 0 0 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 24 0 0 0 24 0 8 8 0 0 0 8 8 8 % I
% Lys: 0 8 16 0 39 0 31 8 8 0 0 16 8 0 0 % K
% Leu: 16 16 0 0 0 0 0 0 0 0 8 0 0 0 8 % L
% Met: 0 0 0 0 8 16 0 0 0 0 0 0 0 0 8 % M
% Asn: 8 0 8 0 8 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 8 0 8 8 8 0 0 8 8 16 8 8 47 0 24 % P
% Gln: 8 0 0 0 8 8 8 8 0 8 0 0 0 0 0 % Q
% Arg: 39 16 0 0 8 8 0 0 0 8 0 0 8 0 0 % R
% Ser: 0 0 16 24 0 0 0 0 8 0 0 0 8 39 0 % S
% Thr: 0 16 8 16 0 16 8 31 0 0 8 8 0 16 8 % T
% Val: 0 8 8 0 0 8 0 0 0 8 16 0 0 8 8 % V
% Trp: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 8 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _